Drug discovery > Basic Research Products & Reviews

The In-Vivo motorised micromanipulator (IVM) was developed to meet the requirements of the most demanding in-vivo applications. High quality materials and precision assembly, along with the super smooth motion and long travel means that the IVM is stable, versatile and low-noise. It’s perfectly suited to electrophysiology and microinjection procedures and is available with single or three axes of motion. Features: • Ultra stab…

The Scientifica Universal Motorised Stage (UMS) provides rapid, accurate and intuitive remote control translation of your microscope around a sample. Designed to be used in combination with a fixed nose microscopy platform, the 400mm x 200mm UMS provides complete microscope support and the 50mm of travel in both the X and Y axes allows you to roam the largest of samples. An optional Z axis focus control is also available provi…

The SIU-102 is an ideal unit for providing cell stimulus in an imaging application. Unfortunately, the SIU-102 is not compatible with electrophysiological applications. This instrument features optical isolation at the input and transformer isolation at the output. Timing pulses can be controlled by any device capable of generating a TTL level positive pulse (for example, a computer with data acquisition). Positive or negati…

The DP-301 is a single channel AC/DC differential pre-amplifier highly suited for EEG, EKG and extracellular recording. High input impedance High common mode rejection Low noise with high gain High tolerance to DC offsets Bandwidth filtering available High Input Z, High CMR High common mode rejection is very important in minimizing electrical interference. The high input resistance of the DP-301 (1012 ohm typical…

Comprehensive electrophysiology data acquisition and analysis software. Provides both sweep-oriented stimulation and continuous data acquisition along with online analysis. Analyses all types of data: patch-clamp I-V, action potentials, minis and single-channel. Includes graphing and layout capability. pCLAMP 10 is shipped with the following:o pCLAMP 10 CD (Part number 1-2700-0167)o pCLAMP 10 USB security key (Part number 1…

* Slices maintained for many hours prior to transfer to recording chamber* Simple to set up and maintain * Many slices supported on FOUR quick-change nylon netsThe Brain Slice Keeper 4 has been designed to pre-incubate brain slices prior to transfer into recording chambers. It consists of FOUR pairs of closely fitting acrylic rings, upper and lower, between which is wedged a sheet of nylon netting. In operation, it is totally…

When Sensitivity and Accuracy are Key

The preferred choice for steady-state and kinetic studies

The QPatch HT and QPatch HTX enable high-throughput patch clamping with 48 parallel recording sites. Automated patch clamping with the same high quality afforded by conventional patch clamping can now be applied in all phases of ion channel drug discovery, including primary screening of focused compound libraries. • Up to 7000 data points per day • Screening and compound profiling • Multi-hole and single-hole mode (QPatch HT…

GeneMapper® Software is a flexible genotyping software package that provides DNA sizing and quality allele calls for all Applied Biosystems electrophoresis-based genotyping systems. This software specializes in multiapplication functionality, including amplified fragment length polymorphism (AFLP®), loss of heterozygosity (LOH), microsatellite, and SNP genotyping analysis. GeneMapper® Software can help users increase data proc…

The Vortex II Precision Series Single Mode Finely-Tuned Lasers provide the most stable open-loop performance available today. Low frequency jitter is combined with narrow linewidth. Choose the TLB-6904-OI for wavelengths from 632.5 to 640 nm. When ordering, please specify the exact center wavelength (to 10 pm) in vacuum. Part number includes complete laser system and the Vortex 6000 Laser Controller. Heads and controllers can…

The next step in automation. Sakura Finetek can now provide your laboratory with a total solution for film coverslipping linked to a multiple slide stainer for both routine and special staining. With the Tissue-Tek® Film® Coverslipper, linked to the Tissue-Tek® Prisma® Automated Slide Stainer, the user can just walk away and unload the Tissue-Tek® Film® after 12 baskets have been coverslipped, by taking out the convenient ca…

Introducing a vacuum filtration system that makes sample preparation easy: the EMD Millipore Samplicity filtration system with Millex Samplicity membrane filters. With the Samplicity® filtration system and Millex Samplicity® membrane filters, EMD Millipore has transformed sample preparation forever. Advantages of the EMD Millipore Samplicity filtration system include:   •  Higher throughput with simultaneous vacuum filtration…

The NEW XSeriesII ICP-MS is the most productive quadrupole ICP-MS available for routine and high performance analytical work.  The ease of use and practical design of the XSeriesII  means that laboratories can acheive their analytical objectives faster, with greater confidence and less 'hands-on' time from the operator.The XSeriesII is a major update the to highly successful X Series ICP-MS, featuring: 3rd Generation Colli…

Thermo Fluoroskan Ascent, a dedicated microplate fluorometer - High sensitivity for a wide variety of fluorometric applications. The Thermo Fluoroskan Ascent features compatibility with 1- to 384- well plate formats and PCR plates, up to three on-board dispensers, an incubator and a shaker. Application areas of Fluoroskan Ascent Calcium flux assays, Reporter gene assays, Immunoassays, FRET assays, Hybridization assays Cell pro…

SelexION differential mobility spectrometry is an effective ion mobility spectrometry tool for improving data quality in the quantitation and characterization of challenging samples requiring advanced analytical selectivity. SelexION on the SCIEX 5500+ series and 6500+ series delivers a new dimension of selectivity and performance for applications requiring the separation of isobaric species, elimination of challenging co-elut…

Get more from your microplate reader with Magellan, the universal reader control and data analysis software from Tecan. Magellan supports the complete line of Tecan microplate readers enabling quick and easy measurements of samples for both first-time and expert users alike. A versatile user interface and powerful data reduction capabilities enable the optimization of sophisticated experimental work as well as making routine t…

FE-SEM for high-quality imaging & advanced analytical microscopy

500 µl, 17,500–76,000 MW range, pI 4.5–8.5, unstained mixture of myoglobin, trypsin inhibitor, CA, GAPDH, actin, BSA, and conalbumin

Pkg of 1 roll, 26.5 cm x 3.8 m, low fluorescence PVDF membrane for immunoblotting

The Invitrogen NativePAGE Bis-Tris Gel System is a precast polyacrylamide mini-gel system that provides sensitive, high-resolution analysis of native proteins and protein complexes for molecular mass estimations, and assessment of purity.

For protein extraction procedures and SDS polyacrylamide gels

Gain entrance to the Raman world today – Stay flexible for emerging challenges tomorrow

Hitachi has manufactured over 1800 Amino Acid Analyzers for over 40 years. The L-8900 is capable of analyzing physiological fluids and protein hydrolysates. If you have special requirements, the L-8900 is capable of a broad range of applications including clinical, food and pharmaceuticals. The L-8900’s unique post-column delivery design mixes the two ninhydrin reagents online just prior to amino acid derivatization which mean…

The UVette fulfils the highest specifications of modern spectrophotometric analysis in the UV range and can be optimally used for sensitive samples and small volumes. Contamination-free!Individually packaged, UVettes are DNA, RNase and protein-free, and are protected from scratches and dust: These are ideal prerequisites for reliable results and safe transport in the lab. Safe and transparent!The plastic material of the UVette…