Drug discovery > Pre-Clinical Development Products & Reviews

The PerFix EXPOSE Kit (Phospho-Epitopes Exposure kit) is a Fast & Easy Procedure for Cell Signaling.

The PerFix-nc Kit (no centrifuge assay Kit) has been developed to enhance the signal-to-noise ratio of intracellular staining and simplify the workload necessary for the sample preparation.

Fits plastic or glass media bottles with 33mm neck sizes. Cellulose acetate (CA) membranes provide fast flow rates and low protein binding and are good for filtering cell culture media. Angled hose connector simplifies vacuum line attachment. Individually packaged, sterile and certified nonpyrogenic. Each system has the membrane material and pore size printed on the unit and is color-coded by membrane type for easy produ…

The Image Analysis is a software program for the analysis and digital storage of data from 1-D, 2-D, 96 well, slot/dot blot and DNA sequencing electrophoretic gel images. Image Analysis combines the convenience and economy of a flatbed scanner with the ease and sophistication of Hitachi Software's programming capabilities. Image Analysis will analyze almost any TIFF gel image from a wide range of sources including, fluoresce…

The miVac Duo Concentrator is suitable for use with a wide range of solvents, from volatile organic solvents through to water and some of the higher boiling point solvents. The Duo is a centrifugal vacuum concentrator compatable for use with variety of sample formats including tubes, microplates, vials and round bottom flasks. Making it an ideal "work-horse" concentrator for the busy lab. Combined with a SpeedTrap and JetRo…

Cellena® is a bioencapsulation portable platform able to encapsulate high molecular weight compounds, microorganisms and cells in homogeneus particles of predictable and controlable size. Designed by Ingeniatrics, it has been specifically developed for biotechnological research. Its performance is based on Flow Focusing® technology. By means of this technology, the elements to be encapsulated are immobilized within a semiperme…

The smallest instrument for small quantities

The DX Tracked Specimen Delivery Service CATEGORY B BIOLOGICAL SUBSTANCES Using our Tracked Specimen service, you can send your Category B biological substances through our dedicated pre 9 am delivery network and enjoy the benefits of safe and compliant packaging, bar-code tracking and confirmation that your items are out for delivery. CATEGORY A SPECIMENS – FOR CATEGORY A INFECTIOUS SAMPLES DX does not carry Category A spe…

Created specifically for solid dosage forms, Parteck® excipients are distinguished by outstanding functionalities and a unique particle structure. All Parteck® products are developed under our Functional Particle Engineering concept comprising advanced EMD Millipore technologies for quite extraordinary functionally relevant particle properties. These properties of Parteck® excipients offer decisive advantages to the formulato…

The AttoPhos® AP Fluorescent Substrate System provides a highly sensitive fluorescent alkaline phosphatase substrate.   The system includes AttoPhos® Substrate, AttoPhos® Buffer and Calibration Solution. AttoPhos® Substrate (2′-[2-benzothiazoyl]-6′-hydroxybenzothiazole phosphate [BBTP]) is cleaved by alkaline phosphatase to produce inorganic phosphate (Pi) and the alcohol, 2′-[2-benzothiazoyl]-6´-hydroxybenzothiazole (BB…

The demand for a more powerful and colder condenser has naturally arisen as the boundaries of evaporation science are pushed further and further. Users increasingly regard as critical the importance of having the right condenser for the job, with the correct power and temperature profile matched to the characteristics of the evaporator. Genevac has developed the super-powerful and super-cold SuperCool 75, in collaboration wit…

Solid Phase Extraction (SPE) is the basis of analytical laboratories. A crucial step of this process is sample preparation. Therefore we know that a clean sample will yield better results. To achieve this goal SiliCycle has designed SiliaPrep, which is a silica based sorbent exempt of fines, and SiliaPrepX, polymeric based sorbent, that can be found in cartridges, well plates and SPME (Solid Phase Micro-Extraction) cartridges…

The MiniBlock® is an easy-to-use reaction block designed for parallel synthesis and screening. Its unique valve body design enables processes where filtration is critical, including solid-phase organic synthesis, use of scavenger resins with solution phase synthesis and parallel purification via Solid-Phase Extraction (SPE).Make the choice many chemists have made to increase productivity, more so than any other similar tool.…

Achieve superior consistency and reliability of sectioning results with the The Thermo Scientific™ Microm™ HM 525 Cryostat. This semi-electronic cryostat with stepper motor advance allows for fast ,stress-free production of high-quality samples. Ergonomically designed, all settings can be set outside of the cryostat chamber.Microm™ HM 525 Cryostat Features: 7 total freezing stations Peltier with four freezing stations…

Registering an API is complex and thus very time-consuming. That’s why we’ve offer EMPROVE® api: high-quality raw materials for use as active pharmaceutical ingredients. EMPROVE® api raw materials are produced according to cGMP guideline ICH Q7. What’s more, all of our EMPROVE® API production plants are located in Western Europe and follow current environmental standards. And in order to support your products’ compliance with…

Raw material qualification is a key factor in assuring the quality and safety of biopharmaceuticals. Even still, performing tests and compiling required documentation on your own is costly and time-consuming. Enter EMPROVE® bio raw materials – your solution for getting products to market faster. EMPROVE® bio raw materials for use in biopharmaceutical production offer specifications adapted for use in upstream or downstream pr…

EMPROVE® exp for use as excipient As drug approval procedures grow stricter, regulatory requirements are becoming more demanding for excipients. Our high-quality EMPROVE® exp raw materials for use as excipients not only comply with relevant regulations, but also come with detailed documentation, facilitating lower costs of qualification, so you can get to market faster. EMPROVE® exp dossiers comprise information on the manuf…

Excellent hardness and fast disintegration for wet granulation formulations Mannitol, a sugar alcohol that predominantly occurs in three crystalline forms (alpha, beta and delta polymorph), is especially suitable as an excipient for advanced, highly active APIs thanks to its non-hygroscopicity and low content of reducing sugars. However, standard mannitol (in beta quality) often lacks sufficient binding and compaction propert…

With today’s faster, leaner production requirements, the smooth integration of pharmaceutical excipients is essential. And since pharmacopeia now specify functionality in addition to chemical purity, Merck Millipore has adopted these challenges in a new addition to the Parteck® family. Parteck® LUB products are vegetable grades of Magnesium stearate, Calcium stearate and Stearic acid, the most effective excipients for lubrica…

Advanced technology for excellent tabletting properties Mannitol is a sugar alcohol that is especially suitable as an excipient for advanced, highly active APIs due to its non-hygroscopicity and low content of reducing sugars. Merck Millipore's outstanding, directly compressible mannitol Parteck® M is your best choice – especially if your tableting aims at rapid release of high-dose or low-dose actives.Parteck® M belongs to t…

Parteck® Mg DC – directly compressible without additives The efficient and safe production of tablets – from drugs to fizzy tablets – requires high-quality excipients, especially if higher ingredient concentrations are needed. The best choice for formulation of such drugs are excipients that are directly compressible because they make it possible to produce sufficiently hard tablets at high quality and with fewer process step…

Merck Millipore’s Parteck® ODT gives formulators the opportunity to produce top-quality, rapid-acting tablets more cost-effectively than ever. These days, people want no-fuss, no-wait solutions – convenience products that work, quickly and without hassle. This is why many patients prefer orally disintegrating tablets, or ODTs.ODTs allow manufacturers to provide fast-acting medication, add value to existing compounds and – imp…

Unique functional particles for excellent tabletting properties Parteck® SI, Merck’s outstanding, directly compressible sorbitol, is available in a variety of particle sizes and qualities for virtually any application you can imagine.The unique particle structure of Parteck® SI – loosely packed, needle-like crystals – gives it some quite distinctive physical properties making Parteck® SI the perfect excipient for combining ma…

Pursue preliminary appraisal of your drug candidate's safety with Covance's Lead Optimization (LO) Toxicology services. Whether your screening needs are for traditional dosing and observation methods or technologically sophisticated services, Covance LO Toxicology services, Safety Assessment and Abuse Liability provides you with sophisticated preclinical measurements of cardiovascular, endocrine, behavioral or neural function…

Capitalize on the intricacies of research questions honed over thousands and thousands of in vivo pharmacology studies conducted by Covance. Procure Covance's in vivo pharmacology expertise and capabilities for your benefit in the design, validation, conduct, and analysis of animal efficacy pharmacology studies for your drug candidates.Lead Optimization Pharmacology Service Features: Assessing and engaging the target tiss…