Assay Services Products & Reviews

Target Deconvolution service based on proteome-wide Cellular Thermal Shift Assay using Mass Spectrometry detection is performed in intact cells and lysate without any compound modifications.

Hit confirmation service is based on the Cellular Thermal Shift Assay (CETSA) and  allows for assessment of compound binding to a selected target protein in its native state without any modifications to the protein or the compound. 

Primary screening based on Cellular Thermal Shift Assay (CETSA) allows for rapid identification of high quality chemical starting points against the native, full-length protein in live cells. 

AbZelect™ and AbZelectPRO™ support cell line development (CLD) to rapidly progress therapeutic protein and recombinant vaccine projects while de-risking the journey to Investigational New Drug (IND) application.

 EpiScreen® – an extensive suite of bioinformatic and primary human cell-based assays for immunogenicity assessment to inform of potential safety and efficacy risks in the clinic.

Monitor the effectiveness of TNF alpha inhibitors adalimumab, infliximab, and etanercept with one automated, cost-effective, and easily accessible assay.

Recombinant antigens and lentivirus for emerging SARS-CoV-2 variants

Celselect™ Slides capture and isolate individual rare cells, or CTCs based on their size

The IDS-iSYS combines 50 years of instrumentation engineering experience with world-respected assay development skills into a compact, benchtop system that fully automates testing of the most challenging calcium, bone, growth and hypertension markers. Uncompromised Efficiency • Full, walk-away automation • Compact, benchtop design • Continuous loading with Batch, Random, and STAT flexibility • Easy operation with auto start-up…

HistologiX is a leading GLP/GCP accredited Contract Research Organisation based in the UK specialising in Histology, Immunohistochemistry (IHC) and Digital Pathology services. HistologiX works with a broad range of clients from big pharma to small and medium biotech companies worldwide. Our team of scientists have in excess of 120 years combined experience and a customer retention rate of 80%. 

Combining the sensitivity of a fluorescence-based assay with a microplate format enables a rapid, quantitative readout suitable for high-throughput analysis. In a microplate well, the fluorescent signal can be generated within whole cells, in cell lysates, or in purified enzyme preparations and may then be analyzed by measuring fluorescence intensity from the well without the need for cellular imaging.

Agilent Resolution ctDx FIRST is a liquid biopsy NGS assay optimized for cancer genomic profiling. ctDx FIRST is an FDA approved companion diagnostic to KRAZATI™ (adagrasib) for the detection of KRAS G12C in non-small cell lung cancer (NSCLC) and provides tumor mutation profiling for single nucleotide variants (SNVs) and deletions in the EGFR gene.

The Agilent Seahorse XF T Cell Metabolic Profiling kit allows for robust and accurate measurements of both glycolytic and mitochondrial activities in T cell populations, providing a complete picture of T cell energy metabolism. These measurements can be linked to antitumor properties of T cell therapy products and are therefore valuable in designing and optimizing therapy development processes to improve T cell persistence or…

Agilent Seahorse Analytics is the newest data analysis application for Agilent Seahorse XF Analyzer products. Seahorse Analytics is built in the cloud, meaning there is no software for you to install, update, or manage. Learn how Seahorse Analytics can make your data analysis experience easier and more enjoyable. Register for a free account and start uploading your assay result files now.

The Agilent Seahorse XF Plasma Membrane Permeabilizer (PMP) is a proprietary reagent that permeabilizes intact cells in culture. It selectively targets the cellular plasma membrane while leaving the mitochondrial membrane intact. This selectivity enables the detailed characterization of key components in mitochondrial function including transporters, enzymes, and electron transport chain complexes.

The Agilent Seahorse XF Palmitate Oxidation Stress Test Kit provides validated reagents to measure long chain fatty acid oxidation (FAO) via assessing changes in oxygen consumption (OCR) in intact cells. The kit includes the XF Palmitate-BSA FAO Substrate, L-carnitine, etomoxir, as well as oligomycin, FCCP, and rotenone/antimycin A to determine the intrinsic rate and capacity of a cell to oxidize palmitate in the absence or l…

Virtual tissues services for biomedical research features high fidelity tissue simulation and modelling to grow virtual tissue from a single cell, giving unprecedented insight into lineage commitment phenomena of stem cells with insight into signalling pathways and detailed gene regulatory networks.With Endogenics complementing traditional techniques, researchers can simulate human cell development and tissue organization and…

Sensitive DNA damage assessment Very low compound requirement Rapid turnaround, ideal for screening Reliable testing by genetic toxicology experts Assay Principles The Comet assay, also called single cell gel electrophoresis, is a technique used for the sensitive detection of DNA damage in individual cells following exposure to a test compound. Electrophoresis is performed on exposed cells that have been embedded i…

Nano BioDiscovery provides a comprehensive line of services for a wide range of proteins, including: • Custom protein array printing • Complete assay development and analysis • Protein profiling services • Technology transfer Each contract service project begins with the client specifying their proteins of interest. NanoInk’s dedicated Contract Research Organization then works in close consultation with the customer to design…

Assays for methylases, acetylases, phosphorylases and other modifying enzymes involved in histone and chromatin modulation are developed and optimized by RapidFire scientists for primary and secondary screens. Although histone modifying enzymes can be difficult to analyze by traditional methods, label-free RapidFire technology is well suited to this novel and emerging class of targets.