Process Chemistry Products & Reviews

p53 inhibitor

PI3K and MEK/ERK pathway inhibitor; Inhibits RasGAP and ERK1

Oleic acid biosynthesis pathway inhibitor; Inhibits stearoyl-CoA desaturase (SCD1)

MEK/ERK pathway inhibitor; Inhibits B-RAF

Tyrosine kinase inhibitor; Inhibits LCK, FYN, HCK, and SRC

Prostanoid pathway activator; Activates prostaglandin receptors EP1, EP2, EP3 and EP4

Hedgehog pathway activator; Activates Smoothened (SMO)

Antibiotic; Protein synthesis inhibitor

Cyclin/CDK pathway inhibitor; Inhibits CDKs

Integrin and tyrosine kinase activator; Activates Integrin, FGFR, IGFR and HER2

NF-?B pathway inhibitor; Inhibits NF-?B

mTOR, PI3K/AKT, NF-kB, and tyrosine kinase pathway inhibitor; Inhibits PI3K and SRC kinases

Immune modulator; TLR7 and TLR8 agonist

Looking to Replace REACH-Restricted NMP? Go Green!

NanoXact Silica Nanospheres - 10 mg/mL or 5 mg/mL  in water, Sizes 20 nm - 1000 nm

NanoXact Silica Nanospheres - Dried Powder, Sizes 80 nm - 1000 nm

BioPure Gold Nanospheres - Bare (Citrate) - 1 mg/mL in water, Sizes 5 nm - 100 nm

Efficiently design, synthesize, characterize and screen libraries of catalyst materials by combining custom hardware and software capabilities. Create and test hundreds of heterogeneous catalyst materials per week using a variety of fully automated techniques. The automated nature of the workflows increase reproducibility and provide a complete experimental record. Prepare: Synthesize diverse arrays of heterogeneous catalyst…

Consistently design, synthesize, screen, and analyze reactions using this automated, high throughput workflow. Significantly increase the number of high quality experiments per year while decreasing experimentation time and manufacturing costs. The Homogeneous Catalysis Workflow utilizes a high pressure reactor (HPR), parallel batch reactor (PBR), and a parallel pressure reactor (PPR) to screen hundreds of reactions per day un…

Perform 48–96 meaningful slurry or solution phase (co)polymerizations per day and increase the productive value of research and development by enabling better decisions, faster. Through the integration of reactor hardware, robotics, and custom software capabilities, the Polyolefins Workflow facilitates 48–96 slurry or solution-phase batch reactor polymerizations with full computer control and in situ temperature and pressure m…

Start-to-finish solution for solubility profiling. The Solubility Workflow enables precise and accurate measurement of the solubility of compounds starting from solid forms or solutions of active pharmaceuticals and intermediates. It is also available in a Benchtop Systems configuration. The Benchtop System is a self-contained, software-driven system, while the integrated workflow connects with other equipment in the lab and s…

Efficiently design, automate and implement consistent forced degradation studies. Quickly identify degradation conditions and potential degradants by automating the testing of solid and solution state samples, while visualizing and recording key variables of degradation experiments. By combining hardware and software capabilities, the Forced Degradation Workflow builds consistent libraries to facilitate data analysis and drive…

Efficiently design, automate, and implement consistent excipient compatibility studies. Quickly identify conditions, potentially incompatible excipients or excipient combinations by automating the testing of solid and solution state samples, while visualizing and recording key variables of excipient experiments. By combining hardware and software capabilities, the Excipient Compatibility Workflow builds consistent libraries to…

Consistently design, synthesize, screen, and analyze reactions using this automated, high-throughput workflow. Significantly increase the number of high quality experiments per year while decreasing experimentation time and manufacturing costs. The Organic Synthesis Workflow utilizes a parallel batch reactor (PBR) to screen hundreds of reactions per day under different stoichiometries, reaction concentrations, and temperature…

Design, implement, and characterize formulations using the automated Adhesives, Coatings and Sealants Workflow Rapidly and precisely formulate libraries, measure and adjust viscosity, prepare thin coatings on various substrates, and measure their properties. The Adhesives, Coatings and Sealants Workflow utilizes multiple Core Modules equipped with liquid handling, heating/stirring, viscometric indexing, and a drawdown tool to…