Process chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.
Color-coded technical buffer solutions in plastic bottles Order No. Type No. pH value at 25 °C Contents285139156 LC 4004 K 4.00 250 ml in PE bottle285139189 LC 7004 K 7.00 250 ml in PE bottle285139218 LC 1004 K 10.00 250 ml in PE bottle Technical buffer solutions according to DIN 19 267 in canisters(preser ved with Thymol…
miVac oil free vacuum pumps can be used with miVac vacuum concentrators or stand alone for use with other suitable vacuum applications in the laboratory. There is a range of three pumps available: Duo pump, 10mbar PTFE diaphragm pump, 38 litres per minute flow rate. Quattro pump, 1mbar PTFE diaphragm pump, 17 litres per minute flow rate. Supoerl pump, 0.3mbar scroll pump, 83 litres per minute flow rate.
Simply multiple: Multi 350i with combined conductivity/oxygen sensor ConOxThe new Multi 350i from WTW, Weilheim, Germany, is a must for anyone who wants to have a versatile high precision multiparameter instrument. In combination with a wide choice of sensors from the WTW program all important parameters of water analysis can be measured: pH, ORP, DO, conductivity, resistance, salinity, TDS, ISE. But there is still more: With…
Portable Measuring: Environmental monitoring, process control and water analysis with pHotoFlex, pHotoFlex Turb and Turb 430 IRWTW has developed a new line of field instruments based on optical measurement, designated pHotoFlex, pHotoFlex Turb and Turb 430 IR. The instruments have been designed to extract the optimum performance from the latest generation optics optics with state-of-the-art LED technology. Using these optics a…
New in the VARIO family of WTW:The VARIO Cond has a lot to offer – at an excellent price. This economically designed meter is ideal for use in process control monitoring or anywhere a small, accurate meter is needed. The VARIO is small, light, handy, waterproof and has a robust firmgrip rubber armoring. Miniature precision, the VARIO Cond Sets:The VARIO Cond KIT with 4 electrodes conductivity cell: The globally renown measuri…
Turb 430 IR is a new portable turbidity meter from WTW, designed for use in the measuring range from 0 – 1100 NTU/FNU. Fully compliant to DIN EN 27027/ISO 7027, the instrument is optimized for applications demanding high mobility, e.g. drinking water analysis and process control. Having been developed together with the multi-parameter photometers of the pHotoFlex Series, the Turb 430 IR offers a number of innovations compared…
WTW has reworked and improved the premium photometers photoLab S6 and S12. The Reference Beam Technology of the WTW filter photometers can technically hardly be topped, especially by the resulting stability and accuracy of measuring. Therefore the focus of the improvement has been on AQA and IQC functionality and also user defined methods for more indiviudal testing: Reading of results as transmittance in %T Storage of 10…
Looking for a portable but precise conductivity measurement to fulfil USP 27 regulations on pure water? For this purpose WTW, Weilheim, Germany, offers the Cond 340i, a precise hand held conductivity meter. It is a instrument including memory, datalogger and RS 232 interface with all features to perform conductivity measurements for every application. For USP measurements the temperature compensation can be switched off, a spe…
As ISP vacuum pumps do not contain lubricating oil or sealing water resulting in no back-migration of fluid, it ensures clean vacuum. It is light-weight and occupies minimum space because of original design called double wrap scroll. While orbiting scroll makes one turn, the process of suction, compression and exhaust proceeds continuously, resulting in a minimum pulsation which provides less vibration and low noise.…
Application Reagent containers for storing up to 3.5 ml of MagNA Pure LC reagents on the stage of the MagNA Pure LC Instrument. The tubs can be sealed with MagNA Pure LC Tub Lids (small, medium) (Cat. No. 03 004 082 001). Quality The disposable plastics for the MagNA Pure LC Instrument meet stringent requirements: they are free of nucleases and amplification inhibitors (for PCR/RT-PCR), and are guaranteed to be inert to…
The Gas Addition Module provides a safe and efficient means of performing gas-liquid reactions under continuous flow-through conditions. Based on an ingenious ‘tube-in-tube’ design developed by scientists at Cambridge University in the UK, it promotes rapid diffusion of pressurized gas through gas-permeable tubing to quickly create a gas saturated solvent stream in typically less than 10 seconds. Liquid (usually in the form of…
Created specifically for solid dosage forms, Parteck® excipients are distinguished by outstanding functionalities and a unique particle structure. All Parteck® products are developed under our Functional Particle Engineering concept comprising advanced EMD Millipore technologies for quite extraordinary functionally relevant particle properties. These properties of Parteck® excipients offer decisive advantages to the formulato…
SiliCycle is a pioneer in metal and organic scavenging solutions. We have nearly two decades of know-how in silica-grafting and scavenging technologies, and the broadest portfolio of scavengers.The removal of post-reaction residues has become a major issue in the pharmaceutical industry, among others. Purification of APIs by traditional methods (chromatography, activated carbon, distillation, etc.) often leads to problems such…
Excellent hardness and fast disintegration for wet granulation formulations Mannitol, a sugar alcohol that predominantly occurs in three crystalline forms (alpha, beta and delta polymorph), is especially suitable as an excipient for advanced, highly active APIs thanks to its non-hygroscopicity and low content of reducing sugars. However, standard mannitol (in beta quality) often lacks sufficient binding and compaction propert…
With today’s faster, leaner production requirements, the smooth integration of pharmaceutical excipients is essential. And since pharmacopeia now specify functionality in addition to chemical purity, Merck Millipore has adopted these challenges in a new addition to the Parteck® family. Parteck® LUB products are vegetable grades of Magnesium stearate, Calcium stearate and Stearic acid, the most effective excipients for lubrica…
Advanced technology for excellent tabletting properties Mannitol is a sugar alcohol that is especially suitable as an excipient for advanced, highly active APIs due to its non-hygroscopicity and low content of reducing sugars. Merck Millipore's outstanding, directly compressible mannitol Parteck® M is your best choice – especially if your tableting aims at rapid release of high-dose or low-dose actives.Parteck® M belongs to t…
Parteck® Mg DC – directly compressible without additives The efficient and safe production of tablets – from drugs to fizzy tablets – requires high-quality excipients, especially if higher ingredient concentrations are needed. The best choice for formulation of such drugs are excipients that are directly compressible because they make it possible to produce sufficiently hard tablets at high quality and with fewer process step…
Merck Millipore’s Parteck® ODT gives formulators the opportunity to produce top-quality, rapid-acting tablets more cost-effectively than ever. These days, people want no-fuss, no-wait solutions – convenience products that work, quickly and without hassle. This is why many patients prefer orally disintegrating tablets, or ODTs.ODTs allow manufacturers to provide fast-acting medication, add value to existing compounds and – imp…
Unique functional particles for excellent tabletting properties Parteck® SI, Merck’s outstanding, directly compressible sorbitol, is available in a variety of particle sizes and qualities for virtually any application you can imagine.The unique particle structure of Parteck® SI – loosely packed, needle-like crystals – gives it some quite distinctive physical properties making Parteck® SI the perfect excipient for combining ma…
Pursue preliminary appraisal of your drug candidate's safety with Covance's Lead Optimization (LO) Toxicology services. Whether your screening needs are for traditional dosing and observation methods or technologically sophisticated services, Covance LO Toxicology services, Safety Assessment and Abuse Liability provides you with sophisticated preclinical measurements of cardiovascular, endocrine, behavioral or neural function…
Capitalize on the intricacies of research questions honed over thousands and thousands of in vivo pharmacology studies conducted by Covance. Procure Covance's in vivo pharmacology expertise and capabilities for your benefit in the design, validation, conduct, and analysis of animal efficacy pharmacology studies for your drug candidates.Lead Optimization Pharmacology Service Features: Assessing and engaging the target tiss…
Obtain critical pharmacokinetic, pharmacodynamic and toxicokinetic assessments with Covance PK/TK Analysis services. Analysis of pharmacokinetics, pharmacodynamics and toxicokinettics data is a critical element in both the preclinical and clinical development of new drugs. Covance retains a dedicated team of highly experienced pharmacokineticists who know how to support your preclinical and clinical studies.PK/TK Analysis Ser…
The Premium Cap is optimally suited for use in the pharmaceutical industry. Two versions are available: packed in Polyethylen bags or STERICLIN®-packed. Without STERICLIN®-packaging the Premium Cap is suitable for dry heat sterilisation up to 260 °C. The sterilisation proof paper is an effective barrier against germs and bacteria, yet it permit the transmission of air, steam, or sterilisation gases.DURAN PURE Premium Cap GL 4…
The DRYPOUR™ packaging system for high-quality hygroscopic salts When it comes to products and workflow, you accept nothing but the highest quality in your production – so the same should apply to packaging. Our DRYPOUR™ packaging system is an outstanding new solution for our high-quality hygroscopic salts.This state-of-the-art design packaging system minimizes caking, thus significantly reducing the time needed for material…
Ready 4 Action, proprietary feasibility assessment, sets the cornerstone of a cost-effective product development plan. Ready 4 Action is the four-step process used to evaluate the viability of proposed drug products. This important tool enables clients to make the go/no-go decision regarding a given drug's market potential and clinical development feasibility.Armed with the neccessary intelligence, uncover with Ready 4 Action…
