Drug discovery > Target Discovery Products & Reviews

The ecTOF is the world’s first GC-HRMS with simultaneous acquisition of EI (Electron Ionization) and CI (Chemical Ionization) information in a single injection. While using EI as the gold-standard GC/MS ionization, the ecTOF in parallel operates a novel CI source. This way it simultaneously provides perfectly aligned accurate mass structural and molecular ion information within a single GC run.

Accelerate precision oncology with Crown Bioscience’s high-quality human biospecimens—comprehensive, clinically annotated samples including tumor tissue, plasma, and PBMCs, optimized for multi-omics research and biomarker discovery.

Cell Line-Derived Xenograft Models, Established multiple in vivo assay systems to evaluate novel anticancer compounds, with each assay specifically designed to understand a drug's mechanism of action, or an individual agent property.

Delve into biomarker discovery and drug development with Crown Bioscience’s next-generation proteomics services—leveraging 4D-DIA technology for deep, reproducible protein profiling and post-translational modification analysis.

Unlock immune insights with Crown Bioscience’s high-throughput flow cytometry—precisely characterize immune cell populations across tissues to elucidate drug mechanisms, assess pharmacodynamics, and optimize immunotherapies.

Accelerate the development of your immuno-oncology drugs with Crown Bioscience’s large panel of immunocompetent syngeneic models.

Crown Bioscience’s preclinical biomarker services help identify, validate, and analyze biomarkers across diverse in vitro and in vivo cancer models. Using multi-omics platforms and expert bioinformatics, these services support drug mechanism studies, patient stratification, and companion diagnostic development to guide oncology drug discovery.

PDX Models Empower your research with models that reflect today’s patients and treatments.

Unlock deeper insights into tissue organization and cellular interactions with Crown Bioscience’s spatial biology and digital pathology services, featuring advanced imaging, automated analysis, and high-throughput biomarker screening for applications in cancer research, immunology, and more.

OrganoidXplore™, Organoid Panel Screening Service

Explore your translational research with Crown Bioscience’s comprehensive genomics services—offering PCR/qPCR, next-generation sequencing, and advanced bioinformatics to deliver high-quality, reproducible data for biomarker discovery and drug development.

Automated filtration and filling system designed to accurately and aseptically aliquot bulk product into multiple biocontainer bags or bottles.

A compact benchtop design that incorporates 2 or 10 individually powered, high-output stirring stations which can prepare samples for content uniformity testing up to 90% faster than conventional methods.​

Rainbow is an in-situ, fiber optic probe-based, concentration monitor that measures concentration and changes in concentration in real-time without the need for sampling.

Sirius T3 measures pKa, log P, and the solubility of ionizable drugs and small molecules using sub-milligram quantities of samples.

Pion’s PAMPA high-throughput permeability assay uses a range of membranes to mimic physiologic conditions. It allows you to evaluate the passive permeability of API’s as well as the absorption potential of simple or complex formulations using robust models and protocols in a 96-well format.

The SCISSOR is an in-vitro subcutaneous injection site simulator that provides biopharma scientists insights into the behavior of their sub-Q drug candidates.

From small-scale R&D to large-scale manufacturing, Pion homogenizers deliver exceptional fluid processing for particle size reduction (micronization,) cell disruption, and the creation of stable micro- and nanoemulsions and dispersions. Built for scalability, we make the transition from lab to commercial production seamless. Trusted by pharmaceutical, biotech, cannabis, chemical, and food and beverage manufacturers worldwide.

The PromoCell Macrophage Generation Media were developed for easy and efficient generation of the full spectrum of M1- and M2-polarized macrophages directly from freshly isolated peripheral blood monocytes.

PromoCell introduces the next generation 3D Tumorsphere Medium. This medium has been designed to meet your requirements for the extended serial culture of tumospheres. Our 3D Tumorsphere Medium supports the culture of the most commonly used cancer cell lines.

Xeno-free medium for the standardized in vitro cultivation of established cancer cell lines.

Serum- and BPE-free medium for an optimal and standardized differentiation of airway epithelial cells at air-liquid interface (ALI).

Fully automated and integrated platform to purify nucleic acids of the highest yield and purity for downstream applications.

MP Magnetic Rack 8 is a novel tool designed for fast and easy extraction of nucleic acids using a magnetic method. It is commonly used in combination with MagBeads FastDNA Kits from MP Biomedicals.