Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
Kainic Acid is a selective agonist of kainite receptors. It is also a potent excitant and neurotoxin. Chemical Name: (2S,3S,4S)-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid M.Wt: 213.23 Formula: C10H15NO4 Solubility: Soluble to 25nM in water Purity: >98% Storage: Store at room temperature
The SureScan Microarray Scanner is a key component of Agilent’s complete microarray solution. With improved feature resolution, it delivers exceptional flexibility to analyze any microarray configuration. The small footprint of the SureScan Microarray Scanner allows lab space to be optimized while improving the sensitivity and maintaining the broadest dynamic range (XDR) currently available on the market. • Continuous loading…
The True MicroChIP kit in combination with the MicroPlex Library Preparation™ kit allows for performing ChIP-seq on as few as 10,000 cells. This microChIP-seq assay has been validated with the new generation IP-Star® Compact Automated Workstation. Furthermore Diagenode's high quality ChIP-seq grade antibodies have been used. Features: Revolutionary: Only 10.000 cells needed for complete ChIP-seq procedure Relia…
Cellmate System takes cell culture processing from the lab bench to high volume without process change. Cellmate is an established system that fully automates all the processes needed to culture cells in roller bottles and T-flasks. It takes cell culture processing from the lab bench to high volume production without process change. The latest generation of Cellmate is supplied with software to support the validation of the s…
The gold standard in bead-based NGS cleanup and size selection
Power and efficiency for large-scale genomics. The HiSeq 2500 System features two run modes, rapid run and high output run mode, and the ability to process one or two flow cells simultaneously. This provides a flexible and scalable platform that supports the broadest range of applications and study sizes. No other system lets you perform so many applications so quickly and easily. Choose between rapid run and high output mode…
The NEBNext® Ultra™ Directional RNA Library Prep Kit for Illumina® contains enzymes and buffers that are ideally suited for cDNA library preparation for next-generation sequencing. NEBNext® reagents are a series of highly pure reagents that facilitate sample preparation of DNA or RNA for downstream applications such as next generation sequencing and expression library construction. The reagents included within these master mi…
The Gallios Flow Cytometer is a research system that delivers analytical excellence by coupling extraordinary sensitivity, resolution and dynamic range with high-speed data collection. Designed to fit your needs, today and tomorrow, the Gallios flow cytometer provides efficient acquisition of excellent quality data from up to 10 colors with advanced optical design for enhanced sensitivity for multicolor assays. With customize…
EZ Read 2000 is the best choice for laboratories that require a microplate reader that can be used for a range of absorbance applications. This versatile microplate reader is capable of measuring samples in many different microplate formats: 12-, 24-, 48- and 96-well plates. The EZ Read 2000 uses tuneable wavelength scanning so that any wavelength can be chosen from 340nm up to 800nm. The EZ Read 2000 is PC-controlled using n…
High quality nucleic acids are a key for downstream applications like genotyping, sequencing and real-time PCR analysis. Together with MACHEREY-NAGEL, we have designed the Genomic STARlet that can run up to eight methods on one instrument to reach minimal variation and optimal standardization. Nucleic acid extraction, isolation and purification from biological samples and PCR products in a non IVD environment. The Genomic STAR…
The easiest NGS Library preparation you will ever find! The MicroPlex Library Preparation™ kit is the only kit on the market which is validated for ChIP-seq and which allows the preparation of indexed libraries from just picogram inputs. In combination with the True MicrochIP kit, it allows for performing ChIP-seq on as few as 10,000 cells. Studies showed a perfect match between the top 40% of peaks and the reference ChIP-…
The Crystal Screen and Crystal Screen 2 reagent kits are designed to provide a highly effective and rapid screening method for the crystallization of macromolecules. The screens are simple and practical for finding initial crystallization conditions. The initial crystallization conditions for more than 1,000 proteins, peptides, oligonucleotides, and small molecules have been determined using Crystal Screen.A highly effective…
Originally published in 1991 by Jancarik & Kim from conditions found to be successful in the crystallization of biological macromolecules. This classic standard sparse matrix screen lets you: Determine initial crystallization conditions. Establish the solubility of a macromolecule in a varying range of pH and precipitants. and with the enhanced buffer selection enables screening of greater crystallization space.Structure Scre…
PEG/Ion, developed by Hampton Research, is a crystallization screen designed to evaluate monodisperse, high purity Polyethylene glycol 3,350 and 48 unique salts representing a very complete range of anions and cations frequently used in the crystallization of biological macromolecules. The primary screening variables are PEG, ion type, ionic strength, and pH. More than 60% of the published crystallizations utilized PEG as a p…
SaltRx was developed by Hampton Research as a primary and secondary, salt and pH based crystallization screen for biological macromolecules. Salt is the only primary crystallization reagent (precipitant) utilized. Based on a design of 96 conditions, the screen evaluates a broad portfolio of crystallization salts of varying concentration and pH.SaltRx can be used as a primary crystallization screen when salt, ionic strength an…
Index is designed as a 96 reagent crystallization screen that combines the strategies of the grid, sparse matrix, and incomplete factorial screening with traditional, contemporary, and new crystallization reagent systems into a highly effective and efficient format. Index, as the name implies, efficiently samples a series of specially formulated reagent zones to identify which reagent class or classes and pH are effective in…
The Opera Phenix ® Plus High-Content Screening System is the premier confocal solution for today' most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera ® and Opera ® Phenix system, the Opera Phenix Plus is designed for high-throughput high-content assays, phenotypic screening, assays using complex disease models, such as live cells, primary cells and microtissues,…
Increase productivity by enabling to grow more cells faster and easier. 3- or 5-layer formats provide 525 cm2 and 875 cm2 cell growth surface area, respectively.Even distribution of media across all layers for homogeneous cell growthAbility to mix cells and reagents in the Falcon Multi-Flask saves time and reduces risk of contaminationFlexible design allows to pour or aspirate/recover cells using a pipetConsistent surface trea…
nanoLiter Cool Wave Dispenser - Major sensitivity and repoducibility increases for ESI & MALDI Nanoliter dispensing devices can be used to place media on the MALDI plates for MALDI/TOF instruments, but the most exciting ability of this device is to collimate droplets directly into the ion source like electrospray (ESI), the unique concept being that nearly 100% of the droplets go directly into the source versus <1% from ESI,…
Magnetic Bead-Based Isolation of Proteins Millipore’s new PureProteome magnetic beads ensure the rapid and reproducible isolation of proteins. Unlike conventional methods that require centrifugation to pellet the beads then careful aspiration to avoid sample loss, PureProteome magnetic beads are isolated using a magnetic rack. This allows for the total removal of buffers for complete recovery of beads no sample dilution. You…
With advanced Q-Drive™ technology, the GeneMate Vortex Mixer provides a smooth instant vortexing of even the largest sample sizes, including full 50ml tubes. The unique counter balance system creates maximum vortexing action, while minimizing noise and excessive vibration. This results in quieter, more efficient and longer lasting operation.GeneMate Vortex Mixer Features: 2-year full replacement warranty! Powerful motor…
Individual reagents from the Grid Screen Ammonium Sulfate and Grid Screen Salt HT screens. Grid Screen Ammonium Sulfate Individual Reagents Features: 185 ml volume Sterile filtered Applications: Individual Grid Screen Ammonium Sulfate and Grid Screen Salt HT screen reagents for screening, optimization and production
The PacBio RS II is a Single Molecule, Real-Time (SMRT®) DNA Sequencing System that provides the highest consensus accuracy and longest read lengths of any available sequencing technology. SMRT Sequencing is ideal for de novo assembly, characterization of genetic variation, methylation analysis, microbiology studies, and more.The instrument features high performance optics, automated liquid handling, and an environmental cont…
