Enzyme Inhibitors Products & Reviews

NHEJ pathway inhibitor; inhibits DNA ligase IV

Epigenetic modifier; Inhibits DNA methyltransferases (DNMTs)

Epigenetic modifier; Inhibitor of Sir2p, SIRT1, and SIRT2

Activin/NODAL/TGF-ß pathway inhibitor; Inhibits SMAD3

JNK pathway inhibitor; Inhibits JNK1, JNK2 and JNK3

Epigenetic modifier; Inhibitor of Sir2p

JAK/STAT pathway inhibitor; Inhibits STAT5

Calcium signaling inhibitor; Inhibits calcium/calmodulin-dependent kinase kinases (CaMKKs)

HGF pathway inhibitor; Inhibits MET

MEK/ERK pathway inhibitor; Inhibits VEGFR2, FGFR1, and PDGFRB

Tyrosine kinase inhibitor; Inhibits of KDR, PDGFR, KIT, RET, FLT-3, ABL and ALK

Cyclin/CDK pathway inhibitor; Inhibits CDK1 and CDK2

Tryosine kinase inhibitor and epigenetic modifier; Inhibits PDGF, FGF, EGF, TGFß, SIRT1, and SIRT5

JAK/STAT pathway inhibitor; Inhibits JAK2

RHO/ROCK pathway inhibitor; Inhibits ROCK

mTOR pathway inhibitor; Inhibits mTORC1 and mTORC2 complexes

Epigenetic modifier; Inhibits lysine-specific demethylase 1 (LSD1)

Epigenetic modifier; Inhibits histone deacetylase (HDAC)1 and HDAC6

WNT pathway activator; Inhibits GSK3ß

MEK/ERK pathway inhibitor; Inhibits MEK1 and MEK2

Epigenetic modifier; Inhibits histone deacetylase (HDAC)1

Tyrosine kinase inhibitor; Inhibits VEGFR1, KDR, FLT-4, EGFR, FGFR, ABL, RET, and SRC

JAK/STAT pathway inhibitor; Inhibits JAK3

JAK/STAT pathway inhibitor; Inhibits JAK3

PI3K/AKT pathway inhibitor; Inhibits PI3K and PLKs