Enzyme Inhibitors Products & Reviews

WNT pathway inhibitor; Inhibits TNKS1 and TNKS2

Epigenetic modifier; Inhibits DNA methyltransferases (DNMT)

Inhibitor of bone resorption; Inhibits farnesyl diphosphate (FPP) synthase

Non-muscle myosin II (NM II) ATPase inhibitor

Ubiquitin-proteasome inhibitor; NF-kB pathway inhibitor; I?B activator

PI3K/AKT pathway inhibitor; Inhibits COX-1 and COX-2

Inhibits glycogen synthase kinase 3ß (GSK3ß)

Prostanoid pathway activator; Inhibits 15-hydroxy PGDH

Epigenetic modifier; Inhibits histone EZH2 lysine methyltransferase

Activates nuclear factor erythroid 2-related factor 2 (Nrf2) protein

Activin/NODAL/TGF-ß pathway inhibitor; Inhibits ALK5, ALK4, and ALK7

AMPK activator

Tyrosine kinase inhibitor; Inhibits EGFR, HER2, JAK2, JAK3 and STAT5a/b

Epigenetic modifier; Inhibits SIRT2 histone deacetylase

PI3K/AKT pathway inhibitor; Inhibits AKT1, AKT2, AKT3

PI3K/AKT pathway inhibitor; Inhibits AKT

Retinoid pathway activator; Activates retinioc acid receptor (RAR) alpha

Epigenetic modifier; Inhibits histone acetyltransferase (HAT)

MEK/ERK pathway inhibitor; Inhibits B-RAF, B-RAFV600E and C-RAF-1

MEK/ERK pathway inhibitor; Inhibits MEK1 and MEK2

mTOR pathway inhibitor; Inhibits mTOR

Inhibits autophagy and vacuolar H+-ATPase (V-ATPase)

WNT pathway activator; Inhibits GSK3

WNT pathway activator; Inhibits GSK3

p38 MAPK inhibitor