HTS Assay Kits Products & Reviews

The SyncroPatch 384 is a revolutionary automated patch clamp system combining high quality electrophysiological data acquisition and analysis with state-of-the-art liquid handling. With 384 amplifier channels and a 384-pipetting head, up to 384 cells can be recorded in parallel, resulting in a throughput of up to 20,000 high-quality data points per day. 

BellBrook Labs Transcreener ® ADP 2 Kinase Assays

BellBrook Labs Transcreener ® AMP 2 /GMP 2 Phosphodiesterase Assays

His-Tag specific labeling for MST using RED-tris-NTA

Universal, HTS Kinase Screening Assays Use higher ATP concentrations: Linear response up to 500μM ATP. Use any kinase and kinase-substrate combination, including peptide, protein, lipid, and sugar substrates. Perform the assay without substrate modifications. Obtain reliable results: Z´-factor values routinely >0.7. Reduce false hits: Luminescence is much less susceptible to interference from library compounds t…

The assay involves two monoclonal antibodies, one labeled with Cryptate and the other with XL665, that recognize distinct determinants. The assay is performed in a single step and requires only a short incubation period. Detection limit of the assay is 0.20 ng/mL and the linear range covers 0.3 to 10 ng/mL. The assay has been validated on various biological material including isolated perfused pancreas, plasma, and pancreatic…

Apoptosis is a normal physiologic process which occurs during embryonic development as well as in maintenence of tissue homeostasis. The apoptotic program is characterized by certain morphologic features, including loss of plasma membrane asymmetry and attachment, condensation of the cytoplasm and nucleus, and internucleosomal cleavage of DNA. Loss of plasma membrane is one of the earliest features. In apoptotic cells, the mem…

For over 30 years CIL has offered a large selection of labeled compounds, including deuterated reagents and solvents

The Luc-Pair™ Duo-Luciferase Assay Kit 2.0 has been improved upon from the Luc-Pair™ Duo-Luciferase Assay Kit. With enhanced stability, it provides a more flexible system in the same convenient 96-well plate format as before for measuring firefly and Renilla luciferases sequentially. Due to its enhanced stability, the Luc-Pair™ Duo-Luciferase Assay Kit 2.0 is the ideal solution for measuring the inhibitory effect of a miRNA on…

Measure Chymotrypsin-, Trypsin- and Caspase-Like Activities

The Caspase-Glo ® 3/7 Assay System is  a highly sensitive caspase activity assay for use in plate-reader assays.

Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies  

A membrane-based antibody array for the parallel determination of the relative levels of selected human cytokines and chemokines. Validated for analyte detection in cell culture supernates, cell lysates, tissue lysates, serum, plasma, saliva, urine, and human milk.

Universal Assay for Serine/Threonine KinasesCisbio's line of HTRF® KinEASE™ STK kits are based on our patented HTRF® technology and can be used as a universal tool for assessing Serine/Threonine kinase activity. These assays use a proprietary antibody and a choice of three biotinylated substrates developed by Upstate to rapidly produce high quality kinase results. Our HTRF KinEASE™ STK kits have been validated on more than 107…

A novel thermoreversible gel mountant for temporary immobilization and imaging.

The proven far-red probe for live or fixed cells, spectrally compatible with UV / Vis-range fluors.

An orange probe staining both nucleus and cytoplasm.

Application The Cell Proliferation Reagent WST-1 is designed to be used for the nonradioactive, spectrophotometric quantification of cell proliferation and viability in cell populations using the 96-well-plate format. It can be used for: Measurement of cell proliferation in response to growth factors, cytokines, mitogens, and nutrients Analysis of cytotoxic and cytostatic compounds, such as anti-cancer drugs and other ph…

Cisbio offers a line of three ready-to-use assays for measuring cAMP using HTRF® technology. Each kit is optimized for detecting a specific range of cAMP concentrations to allow fine tuning of assay sensitivity. These kits enable high quality, cell-based assay screening in 96-, 384- or 1536-well formats.

A novel thermoreversible gel mountant for extended immobilization and imaging.

Functional cell-based assays provide more physiologically useful information compared to binding and non-cellular assays. ChanTest offers cell-based assays to over 90 ion channel targets for screening and profiling for both early discovery and safety liability assessment. Both replicating and division-arrested cell lines are available for most targets which have been validated on a variety of automated electrophysiology plat…

The Amnis NFkB translocation kit includes the conjugated antibody Anti-Hu NFkB (p50) Alexa Fluor 488, the nuclear stain 7-AAD along with the fixation solution, assay buffer and permeabilization buffer to rapidly detect and quantitate NFkB's translocation from the cytoplasm to the nucleus. Nuclear Factor kappa B (NFκB) transcription factor plays a central role in regulating many key processes in mammalian cells, including diff…

Imaging probes conjugated to IRDye 800CW and IRDye 700DX have propelled more than 20 Phase I and Phase II clinical trials worldwide.

BellBrook Labs Transcreener ® UDP² Glycosyltransferase Assays

Three kits to cover a wide range of cAMP concentrations.After the introduction of IP-One, the first HTS immunoassay that can easily detect inositol(1)phosphate (IP1), a stable second messenger which tightly correlates with Gq-coupled receptor activity, the optimization of cAMP assays with the new HTRF® acceptor d2 offers a complete GPCR platform.The upgraded cAMP dynamic 2 and cAMP femto 2 assays, along with the new cAMP HiRa…