UHPLC and HPLC Products & Reviews

Poroshell 120 columns provide rugged, high resolution separations within the pressure range of any mainstream LC system, making the benefits of sub-2 µm performance available with all existing LCs.Poroshell columns can achieve high resolution and high speed separations on current instruments, and higher resolution and speeds on new high-pressure LC and LC/MS systems. Stable to 600 bar, Poroshell 120 are great for fast UHPLC an…

A premium inert range of HPLC columns delivering optimal peak shape. The ProteCol™ range of HPLC columns feature proprietary column designs, incorporating inert materials throughout the flow path and the highest quality stationary phases. The combination of these factors delivers unparalleled separation performance. ProteCol™-P features a PEEK™ lining while ProteCol™-G uses a glass lining. Benefits of an inert flow path are: •…

Streamline your lab operations with a single, secure data system that combines productivity, usability, and data integrity for fast, reliable results.

ChromXP columns optimize performance, ease of use, and reliability of the SCIEX M5 MicroLC, MicroLC 200 Plus and NanoLC 400 systems. ChromXP columns ensure optimum separation and long term stability.  

pH Gradient Buffer Solutions - Simple method development for charge variant characterization Traditionally cation-exchange chromatography using salt gradients has been successfully used to characterize MAb charge variants. However, additional effort is often required to tailor the salt gradient method for individual charge variants. Thermo Scientific™ pH buffer solutions and kits can be used to generate highly reproducible, li…

The Thermo Scientific™ UltiMate™ 3000 HPLC system offers UHPLC compatibility across all modules, ensuring maximum performance. Covering flows from 20 nL/min to 10 mL/min and offering a wide range of pumping, sampling, and detection modules, the UltiMate 3000 series provides solutions for all your chromatography needs. UltiMate 3000 HPLC system Features & Benefits:   UHPLC design for all nano, standard analyt…

Designed for separation of monoclonal antibodies (MAbs) and related biologics by hydrophobic interaction, the Thermo Scientific™ MAbPac™ HIC-10 LC column is a high resolution silica column. The MabPac HIC-10 column's unique chemistry provides high resolution, excellent biocompatibility, and selectivity that is different from other HIC columns on the market. The MAbPac HIC-10 column is based on high-purity, spherical, wide-pore…

DOSE IT – Smart and compact liquid handling The peristaltic pump DOSE IT makes dispensing of culture media, buffers and other solutions easy and efficient. Forget about complicated programming. The setting of all functions and parameters is self-explanatory so that, with minimal learning time, everybody can start working immediately. A broad range of dose volumes can be dispensed with high accuracy since the DOSE IT is compat…

Ensure robust nano and capillary flow LC-MS with Thermo Scientific™ EASY-Spray™ LC Columns

Get improved sensitivity for semivolatile compounds, HPLC/UHPLC compatibility, and a wide flow-rate range in a universal detector. The Thermo Scientific™ Corona™ Veo™ Charged Aerosol Detector widens the envelope of LC conditions for use with capillary, microbore and normal-bore columns to take advantage of ever advancing column technologies. The Corona Veo detector is designed to integrate into any LC, HPLC or UHPLC system fro…

Develop in vitro diagnostic tests with superior resolution. The Thermo Scientific™ Vanquish™ MD HPLC is the ideal chromatographic separations system for laboratories whose analyte resolution is more critical than sample throughput and batch turnaround time. The small, powerful single channel Vanquish MD HPLC meets analytical needs, as well as space and budget limitations.

A highly sensitive, on-line differential viscometer for determining the size and conformation of all types of biopolymers and synthetic polymers.

Reversed Phase Method Development that's Simple, Fast, Effective, and Universal!•Boasts the widest range of reversed phase selectivity in the industry.•Simplifies column selection down to 4 unique stationary phases.•Employs orthogonal selectivity to speed up effective method development.•Maximizes efficacy of your column screening systems.•Fits any HPLC or UHPLC instrumentation. Restek Ultra Selective Liquid Chromatography™ (…

Switch to a Raptor HILIC-Si LC column when you need more retention and resolution of hydrophilic, polar analytes. HILIC silica column designed for increased retention of polar compounds without ion-pairing reagents. 2.7 μm Raptor core-shell particles provide the speed of SPP, with greater efficiency and capacity than 5 μm particles. Ideal for increasing sensitivity and selectivity in LC-MS analyses. Fully compatible with both…

The Ultra line represents Restek’s broadest selection of stationary phases on a single silica support. Made of high-purity, type-B silica that minimizes activity and creates high-density bonding, these columns are designed for selective and reliable HPLC applications. This exceptionally stable C1 phase features our least-retentive reversed-phase hydrocarbon packing. Stationary Phase Category: trimethylsilane (L13) Ligan…

The world’s most advanced multi-detector GPC/SEC system

TSKgel Amide-80 and TSKgel NH2-100 HILIC columns from Tosoh Bioscience are first class columns when it comes to separations of hydrophilic compounds like peptides, carbohydrates, polar natural substances, amino acids, oligonucleotides, organic polar acids and bases, even proteins.

HPLC column

Widely considered the premium columns for analyzing biopolymers by GFC, TSKgel G2000SWXL, 5 μm columns are an excellent choice for small proteins and peptide separations.

The TSKgel Alpha-4000 column is packed with rigid, porous polymer beads which show minimal shrinkage or swelling in polar organic solvents (methanol, acetonitrile, DMSO, isopropanol, THF, and HFIP). This column is stable in a wide variety of organic solvents at concentrations up to 100%.

The TSKgel OligoDNA RP and TSKgel TMS-250 columns incorporate 5 μm or 10 μm spherical porous silica with 250Å pores to allow unhindered access by large oligonucleotides and proteins respectively.

TSKgel STAT columns were designed to increase throughput for high efficiency separations of biomolecules. The nonporous, hydrophilic base material provides superior performance at reduced analysis time.

Silica-based columns are stable and efficient but unsuitable for alkaline analyses due to the silica matrix's weakness under high pH. InertSustain C18, with its novel surface-modified silica, overcomes this limitation. It retains Inertsil's benefits—low back pressure, superior inertness, high efficiency, consistent performance, and wide solvent compatibility—while enabling analyses over a broad pH range.

ZIC®-HILIC HPLC columns for the separation of all classes of polar and hydrophilic compounds. What is HILIC? HILIC or Hydrophilic Interaction Liquid Chromatography is a straightforward chromatographic technique for separation of many types of polar and hydrophilic compounds. To put it simple one can say that HILIC is a normal-phase (NPLC) type of separation but uses reversed-phase (RPLC) type eluents. In HILIC one has: A c…

The base silica of Purospher® STAR columns is 99.999 % pure. Furthermore, meticulous care is given to quality control over all aspects of silica structure and chemistry. The excellent converge of the surface and the purity of the material ensures excellent peak symmetry for acidic, basic and even for chelating compounds. Accurate results with excellent peak shape for all types of analytes Outstanding resolution due…