Drug discovery > Basic Research Products & Reviews

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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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NEBuilder® HiFi DNA Assembly Cloning Kit

New England Biolabs Inc.

NEBuilder® HiFi DNA Assembly Master Mix was developed to improve the efficiency and accuracy of DNA assembly. This method allows for seamless assembly of multiple DNA fragments, regardless of fragment length or end compatibility. This method has been used to assemble either single-stranded oligonucleotides or different sizes of DNA fragments with varied overlaps (15–80 bp). It has utility for the synthetic biology community, a…

5.0/5.0
|7 Reviews

Magnetic mRNA Isolation Kit

New England Biolabs Inc.

The New England Biolabs Magnetic mRNA Isolation Kit is designed to isolate intact poly(A)+ RNA from cells and tissue without requiring phenol or other organic solvents. The technology is based on the coupling of Oligo d(T)25 to 1 μm paramagnetic beads which is then used as the solid support for the direct binding of poly(A)+ RNA. Thus, the procedure permits the manual processing of multiple samples and can be adapted for autom…

5.0/5.0
|1 Review

Gem21 NeuroPlex™ Serum-Free Supplement

GeminiBio

Comparable to B27 ® , Gem21 NeuroPlex™ is a chemically defined, serum-free supplement for use in the culture of neural cells and to promote the differentiation of embryonic stem cells into pancreatic and neuronal lines. When used in conjunction with our NeuroPlex ™ serum-free neuronal medium, this product obviates the need for co-culture with astrocyte feeder cells. Supplied as a 50X concentrate.

5.0/5.0
|1 Review

Alpaqua LE Magnet Plate

alpaqua

The LE Magnet Plate is used with 96-well PCR plates when elution volumes need be kept at a minimum to ensure the highest possible product concentration. This plate allows you to elute in as little as 8-10 µl. The LE Magnet Plate contains a unique plate docking structure and is designed for use with a variety of 96-well PCR plates The LE Magnet Plate is designed for automated* pipetting of 96-well PCR pla…

5.0/5.0
|1 Review

ThermoGrid™ PCR Plates, 96 well Mini Skirt plate, pkg. of 10

Denville Scientific Inc.

Optically Clear for Real Time PCR Raised rim ThermoGrid Plates are rigid, one-piece plates with 0.2ml wells and extremely uniform thin walls for exceptionally rapid temperature transfer from thermal cycler blocks. Each well has a slightly raised rim for compatibility with all types of lid closures and films. The black printed alphanumerics make sample identification easier. All are supplied in natural color and most…

5.0/5.0
|1 Review

3M™ Copper Conductive Tapes - Single Adhesive Surface

Ted Pella Inc.

The tape is easily cut to size and may be quickly applied to a specimen mount or other surface. Carbon or metallic coating normally is applied to the sample and mount. An electrical discharge bridge is then completed from sample, through the copper and its conductive glue to the grounded specimen mount.  The tape is dead soft copper with a conductive acrylic adhesive. It is supplied on a removable liner for easy handling an…

5.0/5.0
|1 Review


Quick Ligation™ Kit

New England Biolabs Inc.

The Quick Ligation™ Kit enables ligation of cohesive end or blunt end DNA fragments in 5 minutes at room temperature. (25°C ) Fast - 5 minutes for cohesive or blunt ends. Convenient - ligation performed at room temperature. Flexible - suitable for all common ligation reactions.

5.0/5.0
|3 Reviews


Prime Thermal Cyclers

Techne, Inc.

The Prime full size thermal cycler delivers high performance, high throughput and maximum flexibility with an ability to upgrade base model to gradient capability with a simple unlock code, as well as the availability of a wide choice of thermal blocks: 0.2ml block (96 x 0.2ml) 0.5ml block (60 x 0.5ml) Combi-Block (33 x 0.2ml and 33 x 0.5ml) 384-well block User friendly programming is achieved via a colour touchscreen…

4.5/5.0
|2 Reviews

Amnis® Imaging Flow Cytometers

Merck

Combining microscopy and flow cytometry, Amnis imaging flow cytometry systems provide bright-field, dark-field (SSC), and several fluorescent images of each cell in flow, at high speed. Paired with IDEAS® software for quantitative image analysis and population statistics, the technology gives you the ability to address complex biology that traditional flow cytometers can't resolve. Not only do the instruments reveal spatial lo…

4.7/5.0
|4 Reviews

Live/Dead Cell Viability Assay Kit (for Mammalian Cells)

BioVision Inc

This assay kit provides an easy-to-use, non-radioactive, histological and FACS-based method for measuring cell proliferation, cell viability, chemotaxis, cytotoxicity and apoptosis. The kit provides a two-color fluorescence method that is based on the simultaneous determination of live and dead cells using two different dyes.  Live cells and intracellular esterase hydrolyzes the dye to produce a hydrophilic, strongly fluore…

4.9/5.0
|2 Reviews

Costar 3596 96-well cell culture plates with lid, flat well, treated, sterile, 50/cs

Cole-Parmer Instrument Co.

Optically clear, virgin polystyrene is treated for optimal cell attachment Stacking beads and uniform footprints (86 x 128 mm) facilitate stacking and handling Serrations on plate flange/skirt enable you to easily distinguish plates from lids when handling stacks of clusters Lids feature individual condensation rings to reduce well-to-well contamination Gamma radiation sterilized and certified pyrogen-free

5.0/5.0
|1 Review

AccuStart II PCR SuperMix

QuantaLife Inc

AccuStart II PCR SuperMix is a 2X concentrated, ready-to-use reaction cocktail for routine PCR amplification of DNA fragments up to 4 kb. It contains all components, except for primers and template.  AccuStart II PCR SuperMix simplifies reaction assembly, improves assay reproducibility, and reduces the risk of contamination. A key component is AccuStart™ II Taq DNA polymerase which contains monoclonal antibodies that bind t…

4.9/5.0
|3 Reviews

Cobra-Stretch Pulsed Dye Lasers

Spectra-Physics

The Cobra-Stretch meets output energy needs up to 250 mJ. Based on a two-stage design, the Cobra-Stretch accommodates an extra amplifier stage to obtain higher powers with either a rectangular cell or capillary amplifiers. An optional auto-tracking bolt-on frequency conversion unit can be used to extend the range of wavelengths. Other harmonic modules can be used to increase the tuning range even further in to the UV and IR.…

5.0/5.0
|2 Reviews

ImmunoSpot® S6 ENTRY

Cellular Technology Limited

The S6 Entry is the baseline model in the CTL Analyzer portfolio. It’s compact design is a real space-saver, but don’t let its small frame fool you. This little Analyzer packs quite a punch. It performs equally as well for standard ELISPOT assays as any of the higher-end models we offer. CTL Analyzers come in a wide range of models, each of which is designed to make assay analysis faster, easier, and more accurate than ever…

4.7/5.0
|3 Reviews

CD133 antibody

Biorbyt

Rabbit polyclonal antibody to CD133; which is also known as prominin or AC133. CD133 is a marker frequently found on multipotent progenitor cells; including immature hematopoietic stem and progenitor cells. The protein has been extensively used as a stem cell marker for normal and cancerous tissues.

4.7/5.0
|2 Reviews