4-Octyl Itaconate
STEMCELL Technologies Inc.Activates nuclear factor erythroid 2-related factor 2 (Nrf2) protein
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Activates nuclear factor erythroid 2-related factor 2 (Nrf2) protein
Activin/NODAL/TGF-ß pathway inhibitor; Inhibits ALK5, ALK4, and ALK7
Tyrosine kinase inhibitor; Inhibits EGFR, HER2, JAK2, JAK3 and STAT5a/b
Retinoid pathway activator; Activates retinioc acid receptor (RAR) alpha
Epigenetic modifier; Inhibits histone acetyltransferase (HAT)
Src family kinases inhibitor; Inhibits Src, LCK, Yes, Cdc2, EGFR, VEGFR, v-Abl, and FAK
Epigenetic modifier; Inhibits histone methyltransferases SU(VAR)3-9
Notch pathway inhibitor; Inhibits Notch receptor and amyloid precursor protein
Activin/NODAL/TGF-ß pathway inhibitor; Inhibits CK1, ALK5 and p38 MAPK