Global DNA Methylation Assay–LINE-1
Active MotifELISA-based assay for the detection and quantification of global DNA methylation in human genomic DNA
Drug discovery > Basic Research Products & Reviews
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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.
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RNA Subcellular Isolation Kit
Active MotifAn efficient method to isolate nuclear and cytoplasmic RNA without cross-contamination
Low Cell Number ChIP-Seq Services
Active MotifEnabling generation of genome-wide binding profiles from as few as 10,000 cells
LightSwitch™ Promoter Reporter GoClone™ Collection
Active MotifFor use with The LightSwitch™ Luciferase Assay System for analysis of promoter regulation
LightSwitch™ 3´UTR Reporter GoClone™ Collection
Active MotifFor use with The LightSwitch™ Luciferase Assay System to measure the impact of a 3´UTR on post-transcriptional regulation
miRNA Target IP Kit
Active MotifDesigned to identify the physical interactions of a miRNA with endogenous mRNA transcripts
TransAM® NFκB Transcription Factor Binding Assays, Family Kit
Active MotifSimple plate-based non-radioactive DNA-binding assays that facilitate the study of NFkB transcription factor activation in mammalian tissue and cell extracts
ChIP-IT® Express Enzymatic Kit
Active MotifComplete solution for convenient, accurate monitoring of protein/DNA interactions
TransAM® Nrf2 Transcription Factor Binding Assay
Active MotifSimple solution for studying Nrf2 activation in human, mouse and rat model systems
ChIP-exo High Resolution ChIP Assay
Active MotifAn optimized and streamlined protocol for high-resolution genome-wide mapping of transcription factor binding sites in the human and mouse genomes
ChIP-IT® FFPE Kit
Active MotifProviding the highest quality ChIP-enriched DNA for analysis by qPCR or Next Generation sequencing
ChIP-IT® PBMC Kit
Active MotifSpecially formulated to perform ChIP from PBMCs, including lymphocytes (T cells, B cells and NK cells), monocytes and dendritic cells
enChIP
Active MotifModified ChIP assay that utilizes the CRISPR/Cas9 system to target a specific DNA locus for immunoprecipitation
DNMT Activity / Inhibition Assay
Active MotifHighly sensitive and rapid microplate-based assay to simplify the measurement of DNA methyltransferase activity
Global 5-hmC Quantification Kit
Active MotifELISA-based assay designed to detect and quantify 5-hydroxymethylcytosine (5-hmC) levels in genomic DNA from different sample types
Histone H3 PTM Multiplex Assay
Active MotifMultiplex epigenetic assay for high throughput profiling of histone post-translational modifications
Total Histone H3 ELISA
Active MotifSimple, sensitive method for detecting changes in histone methylation levels from purified core histones or histones isolated by acid extraction
Hydroxymethyl Collector™
Active MotifDetect and capture DNA fragments containing 5-hydroxymethylcytosine (5-hmC) DNA methylation for analysis
hMeDIP Kit
Active MotifImmunoprecipitate and enrich for DNA fragments containing 5-hydroxymethylcytosine (5-hmC)
MeDIP Kit
Active MotifImmunoprecipitate and enrich for single-stranded DNA fragments containing 5-methylcytosine (5-mC)
MethylCollector™ Ultra
Active MotifFast magnetic assay capable of efficiently isolating methylated CpG islands from fragmented genomic DNA
HypoMethylCollector™
Active MotifNovel technology that allows for positive identification of unmethylated DNA fragments
LightSwitch™ Luciferase Assay Kit
Active MotifReagents to measure luciferase reporter signal as part of the LightSwitch Luciferase Assay System